Poster 70: Using Prazosin to Improve Sleep as the Initial Treatment of Operations Iraqi or Enduring Freedom Veterans With Blast-induced Mild TBI

Poster 70: Using Prazosin to Improve Sleep as the Initial Treatment of Operations Iraqi or Enduring Freedom Veterans With Blast-induced Mild TBI: "We examined whether treatment with sleep hygiene counseling and prazosin would improve sleep, headaches and cognitive performance. Outcome measures were assessed 9 weeks after initiating the intervention and again 6 months later. Results: Only 8% of subjects experienced a side effect (daytime somnolence – 4 subjects, light headedness – 2 subjects). Lightheadedness resolved when prazosin was reintroduced at 0.5mg at bedtime. Nine weeks after starting the intervention, 65 subjects reported restful sleep. Peak headache pain (0–10 scale) decreased from 7.28±0.27 to 4.08±0.19 (P (Source: Archives of Physical Medicine and Rehabilitation)"